Hokkaido University
Faculty of Medicine and Graduate School of Medicine
phone & fax
+81 11 706 5158
+81 11 706 7877
address
N15W7, Kita-ku, Sapporo 060-8638, JAPAN

OUR

Objectives & Strategies

定量解析・操作と創出

形態・機能連関の定量的理解とモデル化
光遺伝学による操作と生命活動の再構成

社会還元

イメージング技術の
臨床応用・社会実装

人材育成

次世代の細胞生理学研究を牽引する
若手人材の育成

Recent Publications

Localization of BCR-ABL to stress granules contributes to its oncogenic function.
Localization of BCR-ABL to stress granules contributes to its oncogenic function.

Kashiwagi S., et al.,
Cell Struct. Funct. 44: 183, 2019

Folding latency of fluorescent proteins affects the mitochondrial localization of fusion proteins.
Folding latency of fluorescent proteins affects the mitochondrial localization of fusion proteins.

Kashiwagi S., et al.,
Cell Struct. Funct. 44: 183, 2019

A peptide derived from phosphoinositide 3-kinase inhibits endocytosis and influenza virus infection.
A peptide derived from phosphoinositide 3-kinase inhibits endocytosis and influenza virus infection.

Fujioka Y., et al.,
Cell Struct Funct 44: 61, 2019

A Sialylated Voltage-Dependent Ca(2+) Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells
A Sialylated Voltage-Dependent Ca(2+) Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells

Fujioka Y., et al.,
Cell Host Microbe 23: 809, 2018

MOVIE GALLERY

visualized by the FRET-based calcium sensor YC3.60

Ca(2+) oscillations induced by IAVs

visualized by the FRET-based calcium sensor YC3.60 in living COS-1 cells
visualized by BiFC

Dynamics of Ras-PI3K complexes induced by EGF stimulation

visualized by BiFC in living COS-1 cells
visualized by the FRET-based biosensor Pickles

Dynamic response to TKIs

visualized by the FRET-based biosensor Pickles in living CML cells